Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(Dicyclohexylphosphino)-2'-methoxy-1,1'-biphenyl

  • CAS No. 255835-82-6

  • Cat. No. CS-0085587
  • Molecule weight380.50
  • Purity≥97%
  • MDL No.MFCD19441234

*For research and further manufacturing use only, not for direct human use.

2-(Dicyclohexylphosphino)-2'-methoxy-1,1'-biphenyl|CS-0085587

Structure of 255835-82-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 255835-82-6
  • Cat. No. CS-0085587
  • Purity ≥97%
  • MDL No. MFCD19441234
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₃₃OP
  • Molecular Weight 380.50
  • Synonym(s) Dicyclohexyl[2-(2-methoxyphenyl)phenyl]phosphane
  • SMILES COC(C=CC=C1)=C1C2=C(P(C3CCCCC3)C4CCCCC4)C=CC=C2

Description

This palladium-docking ligand features a sterically shielded dicyclohexylphosphino group paired with a methoxy-substituted biphenyl backbone, enhancing stability and reactivity in cross-coupling processes. The ortho-methoxy substituent improves solubility and electronic tuning, enabling efficient catalysis under mild conditions.

Application

2-(Dicyclohexylphosphino)-2'-methoxy-1,1'-biphenyl serves as a highly effective ligand in palladium-catalyzed cross-coupling reactions, offering excellent stability and broad functional group tolerance. Its steric and electronic properties facilitate efficient catalytic turnover in Suzuki-Miyaura, Stille, and Negishi couplings. The methoxy substituent enhances solubility and modulates phosphine electronics, improving reactivity in challenging transformations while maintaining bench stability and ease of handling.

Synthesis

  • Route1
    • In-stock
      1-Bromo-2-chlorobenzene|CS-W004051
      694-80-4
    • null|null
      16750-63-3
    • null|null
      16523-54-9
    • ~47%
    • In-stock
      2-(Dicyclohexylphosphino)-2'-methoxy-1,1'-biphenyl|CS-0085587
      255835-82-6

    References

    • Parrish; Buchwald Journal of Organic Chemistry, 2001 , vol. 66, # 11 p. 3820 - 3827

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H317-H319-H335-H360
Precautionary Statements : P261-P264-P271-P272-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   9.23
  • LogP   7.1348
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   5

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 255835-82-6 sigma255835-82-6 manufacturer255835-82-6 price255835-82-6 structure255835-82-6 SDSbuy 255835-82-6255835-82-6 supplier255835-82-6 uses255835-82-6 molecular weightprice of 255835-82-6255835-82-6 chemical name formula of 255835-82-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label