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Structure of 2564-06-9
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N-Benzyl-2-chloroacetamide delivers a reactive chloroacetyl moiety coupled with a benzyl-amide handle, enabling efficient conjugation in bioconjugation workflows. This bench-stable reagent integrates readily into peptide and small-molecule scaffolds under mild conditions, offering selective acylation through nucleophilic substitution.
N-Benzyl-2-chloroacetamide serves as a versatile building block in synthetic organic chemistry, enabling the efficient construction of heterocyclic scaffolds through cyclization reactions. Its chloroacetamide functionality exhibits high reactivity in nucleophilic substitution processes, particularly under mild conditions, and demonstrates excellent bench stability and ease of purification. The benzyl group provides steric and electronic modulation while enhancing solubility in common organic solvents, making it well-suited for use in medicinal chemistry campaigns and process-scale synthesis.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: