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Structure of 2565792-25-6
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This chiral sulfinamide features a strategically positioned diphenylphosphinoaryl group, enabling efficient asymmetric induction in transition-metal-catalyzed reactions. The sterically encumbered tert-butyl sulfonamide moiety enhances configurational stability, while the pendant phosphine ligand facilitates coordination to palladium and other late transition metals. This combination delivers high enantioselectivity in cross-coupling processes under standard conditions.
[S(R)]-N-[(S)-[2-(Diphenylphosphino)phenyl]phenylmethyl]-N,2-dimethyl-2-propanesulfinamide serves as a chiral sulfinamide auxiliary in asymmetric synthesis, enabling stereoselective C–C bond formation via enantioselective α-alkylation and Mannich-type reactions. Its robust bench stability, compatibility with diverse functional groups, and efficient removal under mild conditions make it a practical choice for constructing chiral building blocks in medicinal chemistry workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H413
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Precautionary Statements : P264-P273-P280-P302+P352-P362+P364-P501
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Lot numbers can be found on the outside label of a product: