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Structure of 258515-54-7
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7-Bromo-2-methyl-1,2,3,4-tetrahydroisoquinoline features a brominated heterocyclic core with a methyl substituent at the 2-position, enabling direct functionalization in late-stage diversification. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and bioactive molecule libraries through transition-metal-catalyzed coupling reactions.
7-Bromo-2-methyl-1,2,3,4-tetrahydroisoquinoline serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C7 position via palladium-catalyzed cross-coupling reactions. Its bromine substituent offers high reactivity and compatibility with standard coupling protocols, while the 2-methyl group enhances metabolic stability and modulates electronic properties. The tetrahydroisoquinoline core provides structural rigidity and is commonly found in bioactive molecules, making this compound particularly valuable for scaffold diversification and lead optimization in CNS-targeted drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: