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Structure of 25889-36-5
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3-Nitro-4-(trifluoromethyl)phenol features a strategically positioned nitro group and trifluoromethyl moiety on the phenolic ring, imparting strong electron-withdrawing character and enhanced stability. This combination enables efficient incorporation into advanced synthetic intermediates for pharmaceuticals and agrochemicals, particularly in coupling reactions requiring high reactivity and resistance to decomposition under standard conditions.
3-Nitro-4-(trifluoromethyl)phenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of electron-withdrawing nitro and trifluoromethyl groups into aromatic scaffolds. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient functionalization. The phenolic hydroxyl group allows for derivatization via esterification or ether formation, while the ortho-nitro substituent supports selective transformations under reductive or electrophilic conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: