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Structure of 2598-30-3
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8-Hydroxyquinoline-5-carbaldehyde features a fused quinoline scaffold with strategically positioned hydroxyl and aldehyde groups, enabling chelation of metal ions and serving as a key ligand in coordination chemistry. The electron-deficient aldehyde facilitates nucleophilic addition reactions, while the phenolic OH enhances solubility and stability under standard conditions. This compound integrates readily into functionalized materials and fluorescent probes.
8-Hydroxyquinoline-5-carbaldehyde serves as a versatile bifunctional building block in synthetic medicinal chemistry, enabling efficient construction of quinoline-based scaffolds. The aldehyde group facilitates nucleophilic addition and condensation reactions, while the hydroxyl and quinoline nitrogen provide chelating capability and enhanced solubility. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for modular synthesis of metal-chelating heterocycles and functionalized API precursors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: