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Structure of 25999-04-6
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Morpholine-4-sulfonamide features a morpholine ring tethered to a sulfonamide group, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into medicinal chemistry libraries, offering a polar, hydrogen-bond-capable moiety for optimizing pharmacokinetic profiles in bioactive compound design.
Morpholine-4-sulfonamide serves as a versatile building block in medicinal chemistry, enabling the construction of sulfonamide-containing heterocycles common in kinase inhibitors and other bioactive scaffolds. Its well-defined reactivity facilitates nucleophilic substitution and coupling reactions under standard conditions, with good bench stability and ease of purification. The morpholine ring provides favorable solubility and metabolic properties, enhancing its utility in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: