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Structure of 261635-82-9
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Ethyl 6-chloro-2-(trifluoromethyl)nicotinate features a trifluoromethyl group at the 2-position and a chlorine atom at the 6-position, conferring enhanced electron-withdrawing character and metabolic stability. This bench-stable ester integrates readily into synthetic routes for bioactive heterocycles, particularly in medicinal chemistry applications requiring halogenated pyridine scaffolds.
Ethyl 6-chloro-2-(trifluoromethyl)nicotinate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridine scaffolds. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the chloro substituent facilitates palladium-catalyzed cross-coupling reactions. Its ester functionality supports selective transformations and downstream derivatization, making it well-suited for API development and high-throughput synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: