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CS-W001157 4
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1-Methylimidazoleacetic acid

  • CAS No. 2625-49-2

  • Cat. No. CS-0008620
  • Molecule weight140.14
  • Purity≥97%
  • MDL No.MFCD08668290

*For research and further manufacturing use only, not for direct human use.

1-Methylimidazoleacetic acid|CS-0008620

Structure of 2625-49-2

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General Information

  • CAS No. 2625-49-2
  • Cat. No. CS-0008620
  • Purity ≥97%
  • MDL No. MFCD08668290
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O₂
  • Molecular Weight 140.14
  • Synonym(s) 1-Methylimidazole-4-acetic acid
  • SMILES O=C(CC1=CN(C)C=N1)O

Description

1-Methylimidazoleacetic acid is a bifunctional organic building block featuring a methyl-substituted imidazole ring linked to a carboxylic acid group. This structure enables versatile conjugation chemistry, combining the nucleophilic character of the imidazole with the reactivity of the carboxylate. The molecule exhibits enhanced solubility and stability under standard conditions, facilitating its use in peptide derivatization, catalyst design, and functional material synthesis.

Application

1-Methylimidazoleacetic acid serves as a versatile building block for bioactive heterocycles and peptide conjugates, offering enhanced solubility and metabolic stability. Its imidazole-acetic acid scaffold enables efficient coupling reactions and functions as a key intermediate in the synthesis of targeted therapeutics and catalysts. The molecule exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for high-throughput medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   0.0472
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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