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Structure of 263021-30-3
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This tert-butyl ester derivative of a methylaminobenzoic acid integrates a protected amine and carboxylic acid functionality, enabling sequential deprotection and coupling in peptide synthesis. The electron-withdrawing carbonyl group enhances reactivity at the aromatic ring, while the tert-butoxycarbonyl moiety ensures stability under basic conditions and facilitates selective removal during late-stage functionalization.
4-((tert-Butoxycarbonyl)(methyl)amino)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted benzamide derivatives through standard deprotection and coupling protocols. The tert-butyl carbamate group provides orthogonal protection for primary amines, while the carboxylic acid functionality supports direct amide bond formation or esterification. Its bench-stable nature and compatibility with common reaction conditions facilitate efficient multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H317-H412
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Precautionary Statements : P261-P272-P273-P280-P302+P352-P363-P501
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Lot numbers can be found on the outside label of a product: