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CS-W001157 4
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5-(Morpholin-4-yl)pyridine-3-carboxylic acid

  • CAS No. 263270-06-0

  • Cat. No. CS-0308300
  • Molecule weight208.21
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-(Morpholin-4-yl)pyridine-3-carboxylic acid|CS-0308300

Structure of 263270-06-0

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General Information

  • CAS No. 263270-06-0
  • Cat. No. CS-0308300
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂N₂O₃
  • Molecular Weight 208.21
  • Synonym(s) 5-Morpholin-4-YL-nicotinic acid
  • SMILES C1COCCN1C2=CN=CC(=C2)C(=O)O

Synthesis

  • Route1
    • Methyl 5-morpholinonicotinate|CS-0666170
      500865-54-3
    • ~62%
    • 5-(Morpholin-4-yl)pyridine-3-carboxylic acid|CS-0308300
      263270-06-0

    References

    • MERCK PATENT GMBH; SUTTON, Amanda E.; RICHARDSON, Thomas E.; HUCK, Bayard R.; KARRA, Srinivasa R.; CHEN, Xiaoling; XIAO, Yufang; GOUTOPOULOS, Andreas; LAN, Ruoxi; PERREY, David; VANDEVEER, Harold, George; LIU-BUJALSKI, Lesley; STIEBER, Frank; HODOUS, Brian L.; QIU, Hui; JONES, Reinaldo C.; HEASLEY, Brian Patent: WO2010/93419 A1, 2010 ; Location in patent: Page/Page column 242 ; WO 2010/093419 A1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   62.66
  • LogP   0.6164
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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