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(4R,4'R)-2,2'-(Cyclopropane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)

  • CAS No. 2634687-87-7

  • Cat. No. CS-0104004
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4R,4'R)-2,2'-(Cyclopropane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)|CS-0104004

Structure of 2634687-87-7

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General Information

  • CAS No. 2634687-87-7
  • Cat. No. CS-0104004
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₈N₂O₂
  • Molecular Weight 292.42
  • Synonym(s) None
  • SMILES CC(C)(C)[C@@H]1COC(C2(C3=N[C@H](C(C)(C)C)CO3)CC2)=N1

Description

This cyclopropane-linked bisoxazole features two sterically shielded tert-butyl groups enhancing solubility and stability. The chiral 4,5-dihydrooxazole rings provide a rigid, electron-rich scaffold ideal for asymmetric synthesis and ligand development.

Application

(4R,4'R)-2,2'-(Cyclopropane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole) serves as a stereochemically defined, bench-stable chiral building block for the construction of complex heterocyclic architectures. Its cyclopropane-linked dihydrooxazole units exhibit robust functional group tolerance and enable efficient access to polycyclic scaffolds via standard coupling and cyclization protocols. The tert-butyl groups confer enhanced stability and simplify purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   3.4534
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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