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Structure of 2649470-87-9
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This tetrahydrofuran carboxylic acid features a sterically hindered trifluoromethyl group and a difluoromethoxy-substituted aromatic ring, enhancing metabolic stability and membrane permeability. The chiral framework supports precise stereochemical control in medicinal chemistry applications, enabling efficient incorporation into bioactive scaffolds under standard conditions.
This compound serves as a versatile building block for medicinal chemistry, enabling the synthesis of fluorinated heterocyclic scaffolds relevant to drug discovery. Its structural features—tetrahydrofuran core, trifluoromethyl group, and ortho-difluoro substitution—provide enhanced metabolic stability and lipophilicity. The carboxylic acid functionality facilitates downstream derivatization via amide coupling or esterification, while the stereochemistry ensures predictable reactivity in asymmetric synthesis. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: