3,3',5,5'-Tetramethyl-2,2'-biphenol

Name: 3,3',5,5'-Tetramethyl-2,2'-biphenol
Brand: ChemScene
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CAS No. 26567-10-2
Cat. No. CS-0106526
Purity≥98%
MDL No.MFCD00854202

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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3,3',5,5'-Tetramethyl-2,2'-biphenol|CS-0106526

Structure of 26567-10-2

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Description

3,3',5,5'-Tetramethyl-2,2'-biphenol features a sterically hindered biphenyl scaffold with methyl groups at key ortho positions, enhancing stability and reducing unwanted side reactions. This bench-stable phenolic compound integrates readily into oxidation-sensitive transformations and serves as a robust ligand in catalytic systems requiring electron-rich, protected aromatic frameworks.

Application

3,3',5,5'-Tetramethyl-2,2'-biphenol serves as a sterically hindered phenolic building block for the synthesis of functionalized biphenyl scaffolds. Its methyl substituents enhance bench stability and solubility while enabling selective functionalization at the 2,2′-positions. The compound functions effectively in Ullmann-type coupling reactions and serves as a key intermediate in the construction of chiral ligands and advanced materials.

General Information

CAS No. 26567-10-2
Cat. No. CS-0106526
Purity ≥98%
MDL No. MFCD00854202
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₁₈O₂
Molecular Weight None
Synonym(s) 3,3',5,5'-Tetramethyl-1,1'-biphenyl-2,2'-diol
SMILES OC1=C(C2=CC(C)=CC(C)=C2O)C=C(C)C=C1C

Computational Chemistry Data

TPSA 40.46
LogP 3.99848
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P264-P280-P305+P351+P338-P337+P313

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3,3',5,5'-Tetramethyl-2,2'-biphenol

CAS No. 26567-10-2

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