Lot numbers can be found on the outside label of a product:
Z-D-Ala-OH
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CAS No. 26607-51-2
- Cat. No. CS-W013096
- Purity≥97%
- MDL No.MFCD00063126
*For research and further manufacturing use only, not for direct human use.
Structure of 26607-51-2
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General Information
- CAS No. 26607-51-2
- Cat. No. CS-W013096
- Purity ≥97%
- MDL No. MFCD00063126
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₁H₁₃NO₄
- Molecular Weight 223.23
- Synonym(s) N-Cbz-D-alanine
- SMILES C[C@H](C(O)=O)NC(OCC1=CC=CC=C1)=O
Description
Z-D-Ala-OH is a bench-stable, moisture-tolerant dipeptide building block featuring a protected D-alanine residue. This derivative integrates efficiently into peptide synthesis workflows, offering reliable coupling and minimal side-reaction risk under standard conditions.
Application
Z-D-Ala-OH serves as a key chiral building block in peptide synthesis, offering stable protection of the amine functionality via the benzyloxycarbonyl (Z) group. Its D-alanine configuration enables incorporation into bioactive peptides requiring non-natural amino acid motifs, with excellent bench stability and compatibility in standard coupling protocols. Facilitates efficient N-terminal protection and orthogonal deprotection strategies in complex sequence assembly.
Synthesis
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Route1
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In-stock
338-69-2 -
501-53-1 - ~99%
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In-stock
26607-51-2
References
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Lai, Michelle Y.H.; Brimble, Margaret A.; Callis, David J.; Harris, Paul W.R.; Levi, Mark S.; Sieg, Frank Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 2 p. 533 - 548
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Route2
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565234-19-7
- ~68%
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In-stock
26607-51-2
References
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Harding, Christopher I.; Dixon, Darren J.; Ley, Steven V. Tetrahedron, 2004 , vol. 60, # 35 p. 7679 - 7692
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References
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BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; ARMSTRONG, Daniel, W.; PING, Sun; BREITBACH, Zachary, S.; WANG, Chunlei Patent: WO2010/148191 A2, 2010 ; Location in patent: Page/Page column 45-49; 51 ;
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 75.63
- LogP 1.3859
- H_Acceptors 3
- H_Donors 2
- Rotatable_Bonds 4
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Key Words
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