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CS-W001157 4
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Bis-PEG12-acid

  • CAS No. 2667583-09-5

  • Cat. No. CS-0114772
  • Molecule weight646.72
  • Purity≥98%
  • MDL No.MFCD32207023

*For research and further manufacturing use only, not for direct human use.

Bis-PEG12-acid|CS-0114772

Structure of 2667583-09-5

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General Information

  • CAS No. 2667583-09-5
  • Cat. No. CS-0114772
  • Purity ≥98%
  • MDL No. MFCD32207023
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₈H₅₄O₁₆
  • Molecular Weight 646.72
  • Synonym(s) None
  • SMILES OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O

Description

Bis-PEG12-acid features two terminal carboxylic acid groups flanked by PEG12 chains, delivering enhanced solubility and biocompatibility. This amphiphilic structure enables robust conjugation in aqueous environments, supporting applications in drug delivery, bioconjugation, and surface functionalization with minimal aggregation.

Application

Bis-PEG12-acid serves as a versatile, bifunctional linker for the synthesis of PEGylated compounds and macrocyclic architectures. Its terminal carboxylic acid groups enable straightforward amide or ester conjugation under standard coupling conditions. The long, hydrophilic PEG12 chains confer excellent solubility in aqueous and polar organic media, enhancing bioavailability and reducing aggregation in biological applications. Ideal for drug delivery systems and protein conjugation, it offers robust stability and ease of purification due to its well-defined molecular weight and high purity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   185.36
  • LogP   0.135
  • H_Acceptors   14
  • H_Donors   2
  • Rotatable_Bonds   39

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