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Structure of 27012-25-5
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5-Bromo-2-phenylpyridine is a bench-stable, electron-deficient heterocycle featuring a bromine substituent at the 5-position and a phenyl group at the 2-position. This structural motif enables direct coupling in palladium-catalyzed cross-coupling reactions, serving as a key scaffold for constructing biaryl architectures in medicinal chemistry and materials science applications.
5-Bromo-2-phenylpyridine serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. Its bromine substituent facilitates palladium-catalyzed coupling with boronic acids, amines, and organometallic reagents under standard conditions. The phenylpyridine core provides structural rigidity and enhanced electronic properties, making it suitable for applications in pharmaceutical synthesis and materials science. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: