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CS-W001157 4
Total: USD 88.00

Apixaban impurity 1

  • CAS No. 27143-07-3

  • Cat. No. CS-M1832
  • Molecule weight256.69
  • Purity≥98%
  • MDL No.MFCD02852962

*For research and further manufacturing use only, not for direct human use.

Apixaban impurity 1|CS-M1832

Structure of 27143-07-3

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General Information

  • CAS No. 27143-07-3
  • Cat. No. CS-M1832
  • Purity ≥98%
  • MDL No. MFCD02852962
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₃ClN₂O₃
  • Molecular Weight 256.69
  • Synonym(s) None
  • SMILES Cl/C(C(OCC)=O)=N\NC1=CC=C(OC)C=C1

Synthesis

  • Route1
    • null|null
      104-94-9
    • In-stock
      Ethyl 2-chloroacetoacetate|CS-W018512
      609-15-4
    • ~%
    • In-stock
      Apixaban impurity 1|CS-M1832
      27143-07-3

    References

    • Synthesis, , # 11 p. 1799 - 1803
  • Route2
    • In-stock
      Ethyl 4-chloroacetoacetate|CS-D1440
      638-07-3
    • null|null
      104-94-9
    • ~%
    • In-stock
      Apixaban impurity 1|CS-M1832
      27143-07-3

    References

    • US2006/69258 A1, ; Page/Page column 11-12 ;
  • Route3
    • null|null
      104-94-9
    • null|null
      105-39-5
    • ~%
    • In-stock
      Apixaban impurity 1|CS-M1832
      27143-07-3

    References

    • Farmaco, Edizione Scientifica, , vol. 40, # 4 p. 259 - 271

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331-H341
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.92
  • LogP   2.2225
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   5

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