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Structure of 2725-82-8
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1-Bromo-3-ethylbenzene features a bromine substituent ortho to an ethyl group on the benzene ring, enabling selective cross-coupling reactions. This configuration delivers enhanced regiocontrol in palladium-catalyzed transformations, particularly Suzuki-Miyaura and Stille couplings. The molecule exhibits favorable stability under standard reaction conditions and integrates readily into complex molecular architectures.
1-Bromo-3-ethylbenzene serves as a versatile aryl halide building block in cross-coupling reactions, enabling efficient C–C bond formation under palladium-catalyzed conditions. The ortho-ethyl substituent provides steric and electronic modulation, enhancing regioselectivity in Suzuki-Miyaura and Negishi couplings. Bench-stable and readily purified by distillation, it functions reliably in the synthesis of functionalized biaryls and complex pharmaceutical intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: