H-Leu-OEt.HCl

Name: H-Leu-OEt.HCl
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2743-40-0
Cat. No. CS-W010608
Purity≥97%
MDL No.MFCD00034879

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 2743-40-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 2743-40-0
Cat. No. CS-W010608
Purity ≥97%
MDL No. MFCD00034879
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₈ClNO₂
Molecular Weight 195.69
Synonym(s) None
SMILES CCOC([C@](N)([H])CC(C)C)=O.Cl

Description

H-Leu-OEt·HCl is a bench-stable, moisture-tolerant amino acid ester hydrochloride featuring a protected N-terminal and ethyl ester side chain. This derivative facilitates direct incorporation into peptide synthesis workflows, enabling efficient coupling reactions under standard conditions without requiring additional activation or protection steps.

Application

H-Leu-OEt·HCl serves as a readily handleable, bench-stable amino acid building block for peptide synthesis. Its ethyl ester functionality enables efficient coupling reactions with minimal side-product formation, while the protonated amine ensures good solubility and compatibility in standard coupling protocols. The HCl salt form enhances crystallinity and simplifies purification, making it well-suited for iterative solid-phase and solution-phase peptide assembly.

Synthesis

Route1
- 64-17-5
- 61-90-5
- ~%
- In-stock
  
  2743-40-0
References
- Sun, Chuanwen; Zhu, Jun; Wang, Haifeng; Jin, Jia; Xing, Jiahua; Yang, Dingrong European Journal of Medicinal Chemistry, 2011 , vol. 46, # 1 p. 11 - 20
Route2
- 61-90-5
- ~%
- In-stock
  
  2743-40-0
References
- E. R. Squibb and Sons, Inc. Patent: US4885292 A1, 1989 ;
Route3
- 37787-76-1
- ~%
- In-stock
  
  2743-40-0
References
- Meppen, Malte; Pacini, Barbara; Bazzo, Renzo; Koch, Uwe; Leone, Joseph F.; Koeplinger, Kenneth A.; Rowley, Michael; Altamura, Sergio; Di Marco, Annalise; Fiore, Fabrizio; Giuliano, Claudio; Gonzalez-Paz, Odalys; Laufer, Ralph; Pucci, Vincenzo; Narjes, Frank; Gardelli, Cristina European Journal of Medicinal Chemistry, 2009 , vol. 44, # 9 p. 3765 - 3770

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 52.32
LogP 1.3447
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 4

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Leucine and derivatives

Life Science Amino Acids and their Derivatives C-protected amino acid

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids C-ProtectedAmino Acids

Key Words

H-Leu-OEt.HCl sigmaH-Leu-OEt.HCl manufacturerH-Leu-OEt.HCl priceH-Leu-OEt.HCl structureH-Leu-OEt.HCl SDSbuy H-Leu-OEt.HClH-Leu-OEt.HCl supplierH-Leu-OEt.HCl usesH-Leu-OEt.HCl molecular weightprice of H-Leu-OEt.HClH-Leu-OEt.HCl chemical name formula of H-Leu-OEt.HCl

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

H-Leu-OEt.HCl

CAS No. 2743-40-0

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words