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Structure of 27489-63-0
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Benzyl (trans-4-hydroxycyclohexyl)carbamate features a bench-stable, moisture-tolerant carbamate group that enables selective protection of primary amines. The trans-configured cyclohexyl scaffold provides defined stereochemistry and enhanced solubility in organic media. This reagent streamlines amine derivatization workflows while minimizing epimerization risks during synthesis.
Benzyl (trans-4-hydroxycyclohexyl)carbamate serves as a robust, bench-stable protecting group for primary amines, enabling selective N-alkylation and amide coupling reactions. The trans-4-hydroxycyclohexyl moiety offers enhanced stability and facilitates orthogonal deprotection under mild acidic conditions. Its compatibility with diverse reaction environments makes it particularly valuable in the synthesis of complex heterocycles and peptide-based scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: