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Structure of 27568-05-4
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Ethyl 4-chloro-8-methoxyquinoline-3-carboxylate features a quinoline core with complementary electron-withdrawing and donor substituents, enabling efficient coupling in cross-coupling reactions. The methoxy group enhances solubility and stabilizes reaction intermediates, while the chloro and ester functionalities serve as key handles for further derivatization in medicinal chemistry and materials synthesis.
Ethyl 4-chloro-8-methoxyquinoline-3-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined electrophilic chlorine site. The methoxy group at the C8 position enhances solubility and modulates electronic properties, while the ester functionality supports further derivatization. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient access to substituted quinoline scaffolds relevant to medicinal chemistry and agrochemical research.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: