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Structure of 27741-65-7
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Ethyl 2-cyclobutylideneacetate features a strained cyclobutylidene moiety flanked by an ester group, enabling its use in cycloaddition reactions and as a building block for complex carbocycles. The electron-deficient alkene facilitates Diels-Alder and [2+2] cycloadditions under mild conditions.
Ethyl 2-cyclobutylideneacetate serves as a versatile Michael acceptor and dienophile in synthetic organic chemistry, enabling efficient construction of cyclohexene and cycloheptene scaffolds via Diels-Alder reactions. Its α,β-unsaturated ester functionality exhibits excellent bench stability and compatibility with diverse nucleophiles, facilitating straightforward functionalization and purification. This compound functions as a key building block for complex cyclic architectures in natural product synthesis and medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: