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CS-W001157 4
Total: USD 88.00

tert-Butyl Diethylphosphonoacetate

  • CAS No. 27784-76-5

  • Cat. No. CS-W002322
  • Molecule weight252.24
  • Purity≥98%
  • MDL No.MFCD00075414

*For research and further manufacturing use only, not for direct human use.

tert-Butyl Diethylphosphonoacetate|CS-W002322

Structure of 27784-76-5

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General Information

  • CAS No. 27784-76-5
  • Cat. No. CS-W002322
  • Purity ≥98%
  • MDL No. MFCD00075414
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₁O₅P
  • Molecular Weight 252.24
  • Synonym(s) None
  • SMILES CCOP(=O)(CC(=O)OC(C)(C)C)OCC

Description

Bis-PEG5-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Synthesis

  • Route1
    • null|null
      107-59-5
    • null|null
      762-04-9
    • ~71%
    • In-stock
      tert-Butyl Diethylphosphonoacetate|CS-W002322
      27784-76-5

    References

    • Ye, Wezhen; Liao, Xiugao Synthesis, 1985 , # 10 p. 986 - 988
  • Route2
    • null|null
      5292-43-3
    • null|null
      122-52-1
    • ~97%
    • In-stock
      tert-Butyl Diethylphosphonoacetate|CS-W002322
      27784-76-5

    References

    • Davies, Stephen G.; Fletcher, Ai M.; Roberts, Paul M.; Smith, Andrew D. Tetrahedron, 2009 , vol. 65, # 49 p. 10192 - 10213
  • Route3
    • In-stock
      2-(Diethoxyphosphoryl)acetic acid|CS-W007893
      3095-95-2
    • null|null
      75-65-0
    • ~99%
    • In-stock
      tert-Butyl Diethylphosphonoacetate|CS-W002322
      27784-76-5

    References

    • Shelkov, Rimma; Nahmany, Moshe; Melman, Artem Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 8975 - 8982

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   61.83
  • LogP   2.5942
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   6

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