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Structure of 27996-87-8
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2-Fluoro-5-nitrobenzaldehyde features a fluorine atom at the ortho position and a nitro group at the para position relative to the aldehyde, creating a strongly electron-deficient aromatic ring. This combination enhances reactivity in nucleophilic addition and coupling reactions. The molecule exhibits high stability under standard conditions and integrates readily into complex synthetic sequences requiring polarized electrophilic centers.
2-Fluoro-5-nitrobenzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to substituted aromatic systems. Its ortho-fluoro and meta-nitro substituents provide complementary reactivity for transition-metal-catalyzed coupling reactions and selective reduction sequences. The aldehyde functionality facilitates imine formation, reductive amination, and heterocycle construction under standard conditions. Bench-stable and amenable to purification by recrystallization or column chromatography, it functions reliably in multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: