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CS-W001157 4
Total: USD 88.00

(R)-iPr-iQuinox

  • CAS No. 280755-83-1

  • Cat. No. CS-0087539
  • Molecule weightNone
  • Purity≥95%
  • MDL No.MFCD31568165

*For research and further manufacturing use only, not for direct human use.

(R)-iPr-iQuinox|CS-0087539

Structure of 280755-83-1

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General Information

  • CAS No. 280755-83-1
  • Cat. No. CS-0087539
  • Purity ≥95%
  • MDL No. MFCD31568165
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₆N₂O
  • Molecular Weight None
  • Synonym(s) 1-[(4R)-4,5-Dihydro-4-isopropyl-2-oxazolyl]isoquinoline
  • SMILES CC(C)[C@@H]1COC(C2=NC=CC3=CC=CC=C23)=N1

Description

(R)-iPr-iQuinox is a bench-stable, sterically hindered chiral auxiliary designed for asymmetric synthesis. This iquinoxoline-based scaffold integrates a bulky isopropyl group to enforce high stereocontrol in enantioselective transformations. Its electron-deficient core facilitates efficient coupling reactions while maintaining robust configurational integrity under standard conditions.

Application

(R)-iPr-iQuinox serves as a chiral building block for the synthesis of bioactive heterocycles, enabling stereoselective construction of quinoline and isoquinoline scaffolds. Its isopropyl-substituted indole core exhibits enhanced bench stability and compatibility with standard coupling conditions, facilitating efficient functionalization in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.48
  • LogP   3.0362
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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