Methyl 3-bromo-2-hydroxybenzoate

Name: Methyl 3-bromo-2-hydroxybenzoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 28165-45-9
Cat. No. CS-W022823
Purity≥97%
MDL No.MFCD10566798

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 3-bromo-2-hydroxybenzoate|CS-W022823

Structure of 28165-45-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 28165-45-9
Cat. No. CS-W022823
Purity ≥97%
MDL No. MFCD10566798
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrO₃
Molecular Weight 231.04
Synonym(s) Methyl 3-bromosalicylate
SMILES O=C(OC)C1=CC=CC(Br)=C1O

Description

Methyl 3-bromo-2-hydroxybenzoate features a bromine atom at the meta position relative to the ester, paired with a hydroxyl group ortho to the carbonyl. This dual functionalization enables direct coupling in cross-coupling reactions and facilitates derivatization through the phenolic OH. The compound exhibits good stability under standard bench conditions and integrates readily into synthetic sequences requiring halogenated aromatic intermediates.

Application

Methyl 3-bromo-2-hydroxybenzoate serves as a versatile building block in medicinal chemistry and synthetic organic synthesis, enabling efficient access to substituted benzimidazoles, quinolines, and other heterocyclic scaffolds. The ortho-hydroxyl group facilitates intramolecular cyclization, while the bromide supports palladium-catalyzed cross-coupling reactions. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step sequences requiring functional group compatibility and positional control.

Synthesis

Route1
- 119-36-8
- ~0%
- In-stock
  
  4068-76-2
- In-stock
  
  28165-45-9
References
- Bovonsombat, Pakorn; Ali, Rameez; Khan, Chiraphorn; Leykajarakul, Juthamard; Pla-On, Kawin; Aphimanchindakul, Suraj; Pungcharoenpong, Natchapon; Timsuea, Nisit; Arunrat, Anchalee; Punpongjareorn, Napat Tetrahedron, 2010 , vol. 66, # 34 p. 6928 - 6935
Route2
- 67-56-1
- 854914-90-2
- ~99%
- In-stock
  
  28165-45-9
References
- Dobler, Markus R. Organic and Biomolecular Chemistry, 2004 , vol. 2, # 7 p. 963 - 964
Route3
- 95-56-7
- ~%
- In-stock
  
  28165-45-9
References
- Dobler, Markus R. Organic and Biomolecular Chemistry, 2004 , vol. 2, # 7 p. 963 - 964

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 46.53
LogP 1.9413
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Methyl 3-bromo-2-hydroxybenzoate sigmaMethyl 3-bromo-2-hydroxybenzoate manufacturerMethyl 3-bromo-2-hydroxybenzoate priceMethyl 3-bromo-2-hydroxybenzoate structureMethyl 3-bromo-2-hydroxybenzoate SDSbuy Methyl 3-bromo-2-hydroxybenzoateMethyl 3-bromo-2-hydroxybenzoate supplierMethyl 3-bromo-2-hydroxybenzoate usesMethyl 3-bromo-2-hydroxybenzoate molecular weightprice of Methyl 3-bromo-2-hydroxybenzoateMethyl 3-bromo-2-hydroxybenzoate chemical name formula of Methyl 3-bromo-2-hydroxybenzoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 3-bromo-2-hydroxybenzoate

CAS No. 28165-45-9

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words