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Structure of 28177-69-7
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1-(2-Hydroxy-3-nitrophenyl)ethan-1-one features a phenolic hydroxyl and nitro group ortho to the ketone, enabling intramolecular hydrogen bonding that enhances stability and influences reactivity in electrophilic substitution. This structural motif supports applications in synthetic intermediates for bioactive molecule development and metal chelation studies.
1-(2-Hydroxy-3-nitrophenyl)ethan-1-one serves as a versatile building block in synthetic organic chemistry, enabling the construction of substituted quinoline and isoquinoline scaffolds through well-established cyclization protocols. The ortho-hydroxy nitroaryl ketone functionality facilitates efficient intramolecular reactions under mild conditions, offering excellent bench stability and straightforward purification. Its functional group tolerance supports further derivatization in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: