3-Bromo-5-phenoxypyridine

Name: 3-Bromo-5-phenoxypyridine
Brand: ChemScene
Availability: InStock
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CAS No. 28232-63-5
Cat. No. CS-0060563
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 28232-63-5

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Description

3-Bromo-5-phenoxypyridine is a functionalized pyridine derivative featuring a bromine atom at the 3-position and a phenoxyl group at the 5-position, enabling efficient cross-coupling transformations. This electron-deficient heteroaryl scaffold integrates readily into complex molecular architectures under standard conditions, offering high stability and compatibility with palladium-catalyzed reactions.

Application

3-Bromo-5-phenoxypyridine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. The bromo group at the 3-position provides high reactivity under standard conditions, while the phenoxypyridine core offers excellent functional group tolerance and bench stability. This compound facilitates the construction of biologically relevant heterocyclic scaffolds and conjugated systems in medicinal chemistry and materials science applications.

General Information

CAS No. 28232-63-5
Cat. No. CS-0060563
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₈BrNO
Molecular Weight 250.09
Synonym(s) Pyridine,3-bromo-5-phenoxy
SMILES C1=CC=C(C=C1)OC2=CN=CC(=C2)Br

Computational Chemistry Data

TPSA 22.12
LogP 3.6364
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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3-Bromo-5-phenoxypyridine

CAS No. 28232-63-5

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