Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(Trifluoromethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylic acid

  • CAS No. 2825012-62-0

  • Cat. No. CS-1046904
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(Trifluoromethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylic acid|CS-1046904

Structure of 2825012-62-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

This trifluoromethyl-substituted bicyclic carboxylic acid features a rigid, electron-deficient scaffold ideal for probing steric and electronic effects in medicinal chemistry. The oxabicyclic core provides structural stability, while the para-trifluoromethyl group enhances metabolic resistance and lipophilicity. Designed for direct incorporation into bioactive molecules, it enables precise modulation of pharmacokinetic properties in lead optimization campaigns.

Application

1-(Trifluoromethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylic acid serves as a rigid, electron-deficient bicyclic building block for medicinal chemistry and materials science. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid functionality enables direct coupling or derivatization. The oxabicyclic core provides conformational restraint, facilitating structure-activity relationship studies. Bench-stable and compatible with standard peptide coupling protocols, it functions effectively in diverse synthetic workflows requiring defined spatial orientation and enhanced physicochemical properties.

General Information

  • CAS No. 2825012-62-0
  • Cat. No. CS-1046904
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁F₃O₃
  • Molecular Weight 224.18
  • Synonym(s) None
  • SMILES O=C(C12COC(CC2)(C(F)(F)F)CC1)O

Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.9627
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2825012-62-0 sigma2825012-62-0 manufacturer2825012-62-0 price2825012-62-0 structure2825012-62-0 SDSbuy 2825012-62-02825012-62-0 supplier2825012-62-0 uses2825012-62-0 molecular weightprice of 2825012-62-02825012-62-0 chemical name formula of 2825012-62-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label