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Structure of 28281-76-7
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5-Methoxyisobenzofuran-1,3-dione features a fused bicyclic core with electron-withdrawing carbonyl groups and a methoxy substituent at the 5-position. This configuration imparts enhanced stability and modulates reactivity in Diels-Alder cycloadditions. The compound serves as a valuable dienophile in synthetic routes to complex heterocycles and natural product analogs.
5-Methoxyisobenzofuran-1,3-dione serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted benzofuran derivatives. Its electron-deficient quinone core facilitates Diels-Alder reactions and nucleophilic additions, while the methoxy group enhances solubility and modulates reactivity. Bench-stable and readily purified by recrystallization, it functions reliably in multistep syntheses involving heterocyclic scaffolds and natural product analogs.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: