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CS-W001157 4
Total: USD 88.00

5-Methoxyisobenzofuran-1,3-dione

  • CAS No. 28281-76-7

  • Cat. No. CS-W019718
  • Purity≥98%
  • MDL No.MFCD02670942
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Methoxyisobenzofuran-1,3-dione|CS-W019718

Structure of 28281-76-7

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Description

5-Methoxyisobenzofuran-1,3-dione features a fused bicyclic core with electron-withdrawing carbonyl groups and a methoxy substituent at the 5-position. This configuration imparts enhanced stability and modulates reactivity in Diels-Alder cycloadditions. The compound serves as a valuable dienophile in synthetic routes to complex heterocycles and natural product analogs.

Application

5-Methoxyisobenzofuran-1,3-dione serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted benzofuran derivatives. Its electron-deficient quinone core facilitates Diels-Alder reactions and nucleophilic additions, while the methoxy group enhances solubility and modulates reactivity. Bench-stable and readily purified by recrystallization, it functions reliably in multistep syntheses involving heterocyclic scaffolds and natural product analogs.

General Information

  • CAS No. 28281-76-7
  • Cat. No. CS-W019718
  • Purity ≥98%
  • MDL No. MFCD02670942
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆O₄
  • Molecular Weight 178.14
  • Synonym(s) METHYL N-(DIPHENYLMETHYLENE)-L-SERINATE
  • SMILES O=C1OC(C2=C1C=CC(OC)=C2)=O

Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.0058
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group :
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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