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CS-W001157 4
Total: USD 88.00

2,7-Dibromo-9,9-dimethyl-9H-fluorene

  • CAS No. 28320-32-3

  • Cat. No. CS-W002369
  • Purity≥98%
  • MDL No.MFCD00099471

*For research and further manufacturing use only, not for direct human use.

2,7-Dibromo-9,9-dimethyl-9H-fluorene|CS-W002369

Structure of 28320-32-3

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General Information

  • CAS No. 28320-32-3
  • Cat. No. CS-W002369
  • Purity ≥98%
  • MDL No. MFCD00099471
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₂Br₂
  • Molecular Weight 352.06
  • Synonym(s) 9H-Fluorene, 2,7-dibromo-9,9-dimethyl-
  • SMILES Brc1ccc2c(c1)C(C)(C)c1c2ccc(c1)Br

Application

2,7-Dibromo-9,9-dimethyl-9H-fluorene serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling the construction of conjugated biaryl systems. The sterically protected fluorene core enhances stability and facilitates purification, while the bromine substituents provide high reactivity in Suzuki, Stille, and Negishi couplings. Its defined regiochemistry and bench-stable nature make it ideal for synthesizing complex molecular architectures in materials science and medicinal chemistry applications.

Synthesis

  • Route1
    • In-stock
      2,7-Dibromo-9H-fluorene|CS-W002120
      16433-88-8
    • null|null
      74-88-4
    • ~97%
    • In-stock
      2,7-Dibromo-9,9-dimethyl-9H-fluorene|CS-W002369
      28320-32-3

    References

    • EP1860097 A1, ; Page/Page column 21; 22 ;
  • Route2
    • null|null
      74-88-4
    • ~%
    • In-stock
      2,7-Dibromo-9,9-dimethyl-9H-fluorene|CS-W002369
      28320-32-3

    References

    • WO2006/100896 A1, ; Page/Page column 31-33 ;
  • Route3

    References

    • Journal of the Chemical Society [Section] B: Physical Organic, , p. 975 - 979

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   5.5179
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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