2-Phenylglycine

Name: 2-Phenylglycine
Brand: ChemScene
Availability: InStock
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CAS No. 2835-06-5
Cat. No. CS-W010964
Purity≥96%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 2835-06-5

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Description

2-Phenylglycine serves as a key chiral building block in the synthesis of pharmaceuticals and bioactive molecules. Featuring a phenyl-substituted alpha-carbon, this compound integrates readily into peptide architectures and offers enhanced metabolic stability. The benzylic proton exhibits moderate acidity, enabling selective functionalization under mild conditions.

Application

2-Phenylglycine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of diverse β-phenylalanine derivatives. Its structure supports straightforward functionalization at both the amino and carboxyl termini, with good bench stability and compatibility across standard coupling protocols. The compound functions effectively in peptide synthesis and as a precursor to pharmaceutically relevant heterocyclic scaffolds.

General Information

CAS No. 2835-06-5
Cat. No. CS-W010964
Purity ≥96%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₉NO₂
Molecular Weight 151.16
Synonym(s) DL-α-Phenylglycine
SMILES O=C(O)C(N)C1=CC=CC=C1

Computational Chemistry Data

TPSA 63.32
LogP 0.771
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Bioactive Molecules Natural Products

Life Science Amino Acids and their Derivatives Glycine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids non-Proteinogenic Amino Acids

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2-Phenylglycine

CAS No. 2835-06-5

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