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CS-W001157 4
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2-(Aminooxy)-N,N-dimethylethan-1-amine dihydrochloride

  • CAS No. 2848-78-4

  • Cat. No. CS-0145225
  • Purity≥97%
  • MDL No.MFCD09836447

*For research and further manufacturing use only, not for direct human use.

2-(Aminooxy)-N,N-dimethylethan-1-amine dihydrochloride|CS-0145225

Structure of 2848-78-4

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General Information

  • CAS No. 2848-78-4
  • Cat. No. CS-0145225
  • Purity ≥97%
  • MDL No. MFCD09836447
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₄Cl₂N₂O
  • Molecular Weight 177.07
  • Synonym(s) O-[2-(dimethylamino)ethyl]hydroxylamine dihydrochloride
  • SMILES NOCCN(C)C.[H]Cl.[H]Cl

Description

This aminooxy-functionalized amine features two dimethylamino groups flanking a reactive oxime handle, enabling efficient conjugation in bioorthogonal labeling. The dihydrochloride salt form enhances solubility and stability under standard conditions, simplifying handling in aqueous reaction systems.

Application

2-(Aminooxy)-N,N-dimethylethan-1-amine dihydrochloride serves as a versatile bifunctional building block for the synthesis of oxime derivatives and bioconjugates. Its amine functionality enables facile derivatization, while the aminooxy group facilitates selective oximation reactions under mild conditions. The compound exhibits excellent bench stability and compatibility with common protecting group strategies, making it suitable for iterative synthesis workflows in medicinal chemistry and peptide modification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   38.49
  • LogP   0.2819
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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