Boc-D-HoPro-OH

Name: Boc-D-HoPro-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 28697-17-8
Cat. No. CS-W014189
Purity≥97%
MDL No.MFCD00237380

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 28697-17-8

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Description

Boc-D-HoPro-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a protected D-homoproline scaffold. This building block integrates readily into peptide chains via standard coupling protocols, offering enhanced solubility and reduced aggregation during synthesis. The tert-butoxycarbonyl group enables straightforward deprotection under mild acidic conditions.

Application

Boc-D-HoPro-OH serves as a stable, bench-ready building block for the synthesis of peptidomimetics and bioactive oligomers. The Boc-protected D-homoproline moiety enables efficient incorporation into peptide chains with minimal racemization, offering enhanced conformational control in cyclic and linear sequences. Its robustness under standard coupling conditions and compatibility with orthogonal functional group manipulations make it ideal for iterative solid-phase and solution-phase syntheses.

General Information

CAS No. 28697-17-8
Cat. No. CS-W014189
Purity ≥97%
MDL No. MFCD00237380
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₉NO₄
Molecular Weight 229.28
Synonym(s) Boc-D-Pipecolic acid
SMILES O=C([C@@H]1N(C(OC(C)(C)C)=O)CCCC1)O

Computational Chemistry Data

TPSA 66.84
LogP 1.8606
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Proline and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Boc-D-HoPro-OH

CAS No. 28697-17-8

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