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Structure of 28737-32-8
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3-Chloro-1H-indole-2-carboxylic acid features a chlorinated indole core with a carboxylic acid group at the C2 position, enabling direct conjugation in heterocyclic synthesis. The electron-withdrawing chlorine enhances reactivity in electrophilic substitution and facilitates coupling reactions under standard conditions. This bench-stable derivative serves as a key scaffold for bioactive molecule development.
3-Chloro-1H-indole-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into indole-based scaffolds through standard coupling reactions. Its carboxylic acid group facilitates amide and ester formation under common conditions, while the 3-chloro substituent offers a handle for subsequent cross-coupling or nucleophilic substitution. The compound exhibits good bench stability and is compatible with diverse functional groups, supporting efficient synthesis of complex heterocyclic systems and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: