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CS-W001157 4
Total: USD 88.00

3,6-Dihydropyran-4-boronic acid pinacol ester

  • CAS No. 287944-16-5

  • Cat. No. CS-B0643
  • Molecule weight210.08
  • Purity≥97%
  • MDL No.MFCD11052631

*For research and further manufacturing use only, not for direct human use.

3,6-Dihydropyran-4-boronic acid pinacol ester|CS-B0643

Structure of 287944-16-5

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General Information

  • CAS No. 287944-16-5
  • Cat. No. CS-B0643
  • Purity ≥97%
  • MDL No. MFCD11052631
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉BO₃
  • Molecular Weight 210.08
  • Synonym(s) 2-(3,6-Dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • SMILES CC1(C)OB(C2=CCOCC2)OC(C)1C

Description

Methyltetrazine-NHS Ester is a NHS actived building block containing a methyltetrazine group. It can react with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene).

Synthesis

  • Route1

    References

    • WO2008/153858 A1, ; Page/Page column 307 ; WO 2008/153858 A1
  • Route2
    • null|null
      1295521-64-0
    • ~96%
    • In-stock
      3,6-Dihydropyran-4-boronic acid pinacol ester|CS-B0643
      287944-16-5

    References

    • WO2011/50016 A1, ; Page/Page column 108 ; WO 2011/050016 A1
  • Route3
    • null|null
      25015-63-8
    • In-stock
      3,6-Dihydro-2H-pyran-4-yl trifluoromethanesulfonate|CS-B0642
      188975-30-6
    • ~%
    • null|null
      1173199-90-0
    • In-stock
      3,6-Dihydropyran-4-boronic acid pinacol ester|CS-B0643
      287944-16-5

    References

    • Journal of the American Chemical Society, , vol. 131, # 28 p. 9612 - 9613

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   1.9645
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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