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Structure of 288386-04-9
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4-Fluoro-5-hydroxyindole features a hydroxyl group at the 5-position and a fluorine atom at the 4-position of the indole core, creating a uniquely polarized aromatic system. This configuration enhances solubility while maintaining metabolic stability. The compound serves as a key scaffold for bioactive molecule synthesis, particularly in CNS-targeted pharmaceuticals and fluorescent probes.
4-Fluoro-5-hydroxyindole serves as a versatile building block for the synthesis of biologically active indole derivatives, particularly in medicinal chemistry and pharmaceutical research. Its ortho-hydroxy and fluoro substituents enable selective functionalization and enhanced metabolic stability. The compound exhibits good bench stability and facilitates straightforward derivatization via coupling reactions, oxidation, or electrophilic substitution, making it well-suited for constructing complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: