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Structure of 28957-72-4
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8-Benzyl-8-azabicyclo[3.2.1]octan-3-one is a sterically constrained, nitrogen-containing bicyclic ketone featuring a benzyl-substituted azabicycle scaffold. This structure integrates a rigid framework with a pendant aromatic group, enabling precise spatial control in synthetic applications. The molecule exhibits enhanced stability and compatibility under standard bench conditions, making it suitable for use in medicinal chemistry and complex molecular assembly workflows.
8-Benzyl-8-azabicyclo[3.2.1]octan-3-one serves as a versatile scaffold in medicinal chemistry, enabling the construction of constrained piperidine analogs via standard reduction and functionalization protocols. Its bicyclic core exhibits robust bench stability and tolerates diverse reaction conditions, facilitating efficient derivatization at the C3 carbonyl and benzylic positions. The molecule functions effectively as a building block for G-protein-coupled receptor (GPCR) ligands and other bioactive architectures requiring rigidified nitrogen-containing frameworks.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: