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CS-W001157 4
Total: USD 88.00

2-Chlorobenzenesulfonyl chloride

  • CAS No. 2905-23-9

  • Cat. No. CS-0072922
  • Purity≥95%
  • MDL No.MFCD00051520
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chlorobenzenesulfonyl chloride|CS-0072922

Structure of 2905-23-9

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Description

2-Chlorobenzenesulfonyl chloride is a reactive sulfonyl chloride reagent featuring a chlorine-substituted benzene ring, enabling efficient sulfonation and functionalization in synthetic organic chemistry. This bench-stable derivative facilitates direct incorporation of sulfonyl groups into complex architectures with high regioselectivity.

Application

2-Chlorobenzenesulfonyl chloride serves as a versatile sulfonylating agent for the efficient introduction of sulfonamide functionalities. It facilitates direct N-sulfonation of amines under mild conditions, exhibits good bench stability, and enables straightforward purification due to its low volatility. The ortho-chloro substituent enhances electrophilicity and provides compatibility with subsequent functional group manipulations, making it well-suited for building blocks in medicinal chemistry and heterocyclic synthesis.

General Information

  • CAS No. 2905-23-9
  • Cat. No. CS-0072922
  • Purity ≥95%
  • MDL No. MFCD00051520
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄Cl₂O₂S
  • Molecular Weight 211.07
  • Synonym(s) o-Chlorobenzenesulfonyl chloride
  • SMILES O=S(C1=CC=CC=C1Cl)(Cl)=O

Computational Chemistry Data

  • TPSA   34.14
  • LogP   2.2675
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2921
Class : 8
Packing Group : Ⅱ
Hazard Statements : H226-H314
Precautionary Statements : P210-P233-P240-P280-P280

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