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Structure of 2919-23-5
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Cyclobutanol is a strained four-membered cyclic alcohol featuring a hydroxyl group bonded to a highly reactive cyclobutane ring. This structural rigidity imparts unique reactivity in synthetic transformations, enabling selective functionalization under mild conditions. The molecule exhibits enhanced polarity compared to its acyclic counterparts, improving solubility in polar solvents while maintaining compatibility with standard anhydrous protocols.
Cyclobutanol serves as a versatile building block in synthetic organic chemistry, enabling the construction of strained cyclic systems and functionalized intermediates. Its hydroxyl group facilitates standard transformations such as oxidation, substitution, and protection, while the cyclobutane ring provides unique conformational constraints valuable in medicinal chemistry. Bench-stable and amenable to purification by distillation or chromatography, it functions reliably in multi-step syntheses requiring controlled reactivity and moderate ring strain.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1987
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Class : 3
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Packing Group : Ⅱ
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Hazard Statements : H225
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501
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Lot numbers can be found on the outside label of a product: