H-DL-Phe(4-NO2)-OH

Name: H-DL-Phe(4-NO2)-OH
Brand: ChemScene
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CAS No. 2922-40-9
Cat. No. CS-W015121
Purity≥98%
MDL No.MFCD00007384

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 2922-40-9

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Description

H-DL-Phe(4-NO2)-OH features a para-nitro-substituted phenylalanine scaffold with enhanced electron-withdrawing character, enabling precise tuning of reactivity in peptide synthesis. This bench-stable derivative integrates readily into complex sequences under standard conditions, offering improved solubility and compatibility in aqueous and organic media.

Application

H-DL-Phe(4-NO₂)-OH serves as a versatile building block for peptide synthesis, enabling the incorporation of a para-nitrophenylalanine residue with defined stereochemistry. The nitro group provides a robust handle for downstream transformations, including reduction to an amino group or participation in metal-catalyzed coupling reactions. Its stability under standard peptide coupling conditions and compatibility with common protecting group strategies make it a practical choice for synthesizing functionalized peptides and heterocyclic scaffolds.

General Information

CAS No. 2922-40-9
Cat. No. CS-W015121
Purity ≥98%
MDL No. MFCD00007384
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀N₂O₄
Molecular Weight 210.19
Synonym(s) None
SMILES NC(C(O)=O)CC1=CC=C([N+]([O-])=O)C=C1

Computational Chemistry Data

TPSA 106.46
LogP 0.5492
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

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H-DL-Phe(4-NO2)-OH

CAS No. 2922-40-9

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