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CS-W001157 4
Total: USD 88.00

(2-Fluorophenyl)hydrazine hydrochloride

  • CAS No. 2924-15-4

  • Cat. No. CS-W016106
  • Purity≥96%
  • MDL No.MFCD00012927

*For research and further manufacturing use only, not for direct human use.

(2-Fluorophenyl)hydrazine hydrochloride|CS-W016106

Structure of 2924-15-4

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General Information

  • CAS No. 2924-15-4
  • Cat. No. CS-W016106
  • Purity ≥96%
  • MDL No. MFCD00012927
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈ClFN₂
  • Molecular Weight 162.59
  • Synonym(s) FluorophenylhydrazineHydrochloride
  • SMILES FC1=CC=CC=C1NN.Cl

Description

(2-Fluorophenyl)hydrazine hydrochloride offers a fluorinated aryl scaffold for constructing heterocycles and functionalized biaryls. This bench-stable, moisture-tolerant reagent integrates readily into transition-metal-catalyzed couplings and cyclization cascades, enabling efficient access to pharmacologically relevant scaffolds.

Application

(2-Fluorophenyl)hydrazine hydrochloride serves as a versatile building block for the synthesis of fluorinated heterocycles, particularly in the construction of quinazolines and other nitrogen-containing scaffolds. Its well-documented reactivity enables efficient cyclization under mild conditions, with good bench stability and ease of handling. The compound functions effectively in standard hydrazine-based transformations, offering predictable regioselectivity and compatibility with common functional groups in medicinal chemistry workflows.

Synthesis

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    • In-stock
      (2-Fluorophenyl)hydrazine hydrochloride|CS-W016106
      2924-15-4

    References

    • Archiv der Pharmazie (Weinheim, Germany), , vol. 327, # 2 p. 99 - 104

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   1.5331
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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