4-Bromo-2-fluorobenzamide

Name: 4-Bromo-2-fluorobenzamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 292621-45-5
Cat. No. CS-0015688
Purity≥97%
MDL No.MFCD03094432

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 292621-45-5

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Description

4-Bromo-2-fluorobenzamide features a strategically positioned bromine and fluorine substituent on the benzamide core, enabling selective functionalization in late-stage synthesis. This electron-deficient aromatic scaffold integrates readily into pharmaceutical intermediates and bioactive molecules, offering enhanced metabolic stability and predictable reactivity under standard coupling conditions.

Application

4-Bromo-2-fluorobenzamide serves as a versatile building block in medicinal chemistry and cross-coupling synthesis. Its ortho-halogenated aromatic core enables reliable Suzuki, Stille, and Negishi couplings, while the amide functionality offers synthetic handle for derivatization. Bench-stable and readily purified by crystallization, it facilitates efficient access to substituted heterocycles and pharmaceutical intermediates.

General Information

CAS No. 292621-45-5
Cat. No. CS-0015688
Purity ≥97%
MDL No. MFCD03094432
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅BrFNO
Molecular Weight 218.02
Synonym(s) None
SMILES FC1=C(C(N)=O)C=CC(Br)=C1

Computational Chemistry Data

TPSA 43.09
LogP 1.6871
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amide

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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4-Bromo-2-fluorobenzamide

CAS No. 292621-45-5

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