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CS-W001157 4
Total: USD 88.00

Pyrazolo[1,5-a]pyrimidin-5-ol

  • CAS No. 29274-22-4

  • Cat. No. CS-0036458
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Pyrazolo[1,5-a]pyrimidin-5-ol|CS-0036458

Structure of 29274-22-4

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Description

Pyrazolo[1,5-a]pyrimidin-5-ol features a fused heterocyclic core with a phenolic hydroxyl group, enabling hydrogen bonding and enhanced solubility in polar solvents. This scaffold exhibits robust stability under standard bench conditions and serves as a key building block in medicinal chemistry, particularly for kinase inhibitors and bioactive small molecules.

Application

Pyrazolo[1,5-a]pyrimidin-5-ol serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling rapid access to biologically active compounds through established functionalization at the C5 position. Its inherent stability and compatibility with standard coupling reactions facilitate efficient derivatization for target-focused library synthesis. The molecule functions as a key building block in the development of kinase inhibitors and other bioactive agents, offering predictable reactivity and favorable purification characteristics in routine laboratory workflows.

General Information

  • CAS No. 29274-22-4
  • Cat. No. CS-0036458
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅N₃O
  • Molecular Weight 135.12
  • Synonym(s) pyrazoloapyrimidinone
  • SMILES OC1=NC2=CC=NN2C=C1

Computational Chemistry Data

  • TPSA   50.42
  • LogP   0.4349
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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