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CS-W001157 4
Total: USD 88.00

Methyl 3,5-bis(bromomethyl)benzoate

  • CAS No. 29333-41-3

  • Cat. No. CS-0045310
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 3,5-bis(bromomethyl)benzoate|CS-0045310

Structure of 29333-41-3

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General Information

  • CAS No. 29333-41-3
  • Cat. No. CS-0045310
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀Br₂O₂
  • Molecular Weight 321.99
  • Synonym(s) None
  • SMILES O=C(OC)C1=CC(CBr)=CC(CBr)=C1

Description

Methyl 3,5-bis(bromomethyl)benzoate features two bromomethyl groups flanking a methyl ester on a benzene ring, enabling dual functionalization in synthetic sequences. This electron-deficient aromatic scaffold facilitates nucleophilic substitution and cross-coupling reactions under standard conditions. The compound's bench-stable nature supports reliable handling in multi-step syntheses.

Application

Methyl 3,5-bis(bromomethyl)benzoate serves as a versatile bis-electrophilic building block for the construction of symmetric and functionalized heterocyclic scaffolds. The bromomethyl groups enable efficient alkylation, Suzuki-Miyaura coupling, and nucleophilic substitution reactions under mild conditions. Its bench-stable nature and compatibility with diverse reaction environments facilitate straightforward purification and integration into multi-step synthetic sequences, making it ideal for medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   3.263
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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