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Structure of 29421-73-6
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3,5-Dibromo-2-methylthiophene is a brominated thiophene derivative featuring two bromine substituents at the 3 and 5 positions and a methyl group at the 2 position. This electron-deficient heterocycle integrates readily into cross-coupling reactions, offering high functional group tolerance and stability under standard conditions. The para-bromine pairs enable sequential derivatization, while the methylthio moiety enhances solubility and modulates reactivity in synthetic sequences.
3,5-Dibromo-2-methylthiophene serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its brominated positions enable palladium-catalyzed cross-coupling reactions with broad functional group tolerance, while the methylthio group offers stability and mild reactivity. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: