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CS-W001157 4
Total: USD 88.00

1-Phenylcyclopropan-1-ol

  • CAS No. 29526-96-3

  • Cat. No. CS-0056020
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Phenylcyclopropan-1-ol|CS-0056020

Structure of 29526-96-3

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General Information

  • CAS No. 29526-96-3
  • Cat. No. CS-0056020
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O
  • Molecular Weight 134.18
  • Synonym(s) 1-Phenylcyclopropanol
  • SMILES C1CC1(C2=CC=CC=C2)O

Description

1-Phenylcyclopropan-1-ol features a strained cyclopropyl ring fused to a phenyl group, delivering high reactivity for ring-opening transformations. This bench-stable alcohol integrates readily into synthetic sequences requiring stereoselective functionalization. The hydroxyl-bearing carbon resides at the bridgehead position, enabling controlled derivatization under mild conditions.

Application

1-Phenylcyclopropan-1-ol serves as a valuable chiral building block in synthetic organic chemistry, offering a rigid, strained cyclopropane scaffold with a tertiary alcohol functionality. Its stability under standard reaction conditions enables selective functionalization at the hydroxyl group, facilitating transformations such as derivatization, oxidation, or substitution. The molecule functions effectively in asymmetric synthesis and provides access to complex polycyclic architectures relevant to medicinal chemistry and natural product synthesis.

Synthesis

  • Route1
    • null|null
      93-58-3
    • null|null
      2386-64-3
    • ~94%
    • 1-Phenylcyclopropan-1-ol|CS-0056020
      29526-96-3

    References

    • Eisch, John J.; Adeosun, Adetenu A.; Gitua, John N. European Journal of Organic Chemistry, 2003 , # 24 p. 4721 - 4727
  • Route2

    References

    • Rubottom,G.M.; Lopez,M.I. Journal of Organic Chemistry, 1973 , vol. 38, # 11 p. 2097 - 2099
  • Route3
    • null|null
      93-58-3
    • null|null
      54509-73-8
    • null|null
      2386-64-3
    • ~75%
    • 1-Phenylcyclopropan-1-ol|CS-0056020
      29526-96-3

    References

    • Eisch, John J.; Adeosun, Adetenu A.; Gitua, John N. European Journal of Organic Chemistry, 2003 , # 24 p. 4721 - 4727

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.668
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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