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CS-W001157 4
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m-PEG4-PFP ester

  • CAS No. 2952895-31-5

  • Cat. No. CS-0148098
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

m-PEG4-PFP ester|CS-0148098

Structure of 2952895-31-5

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Description

m-PEG4-PFP ester features a hydrophilic PEG4 spacer flanked by a reactive pyridine-2,4-difluorophenyl (PFP) ester group, enabling efficient conjugation to primary amines under mild conditions. This bench-stable reagent facilitates site-specific labeling of biomolecules with minimal aggregation and enhanced solubility in aqueous environments.

Application

m-PEG4-PFP ester serves as a stable, water-soluble coupling reagent for amine functionalization, enabling efficient conjugation under physiological conditions. Its PFP ester moiety reacts selectively with primary amines to form robust amide bonds, while the central m-PEG4 spacer provides enhanced solubility and reduced steric hindrance. Ideal for bioconjugation workflows requiring precise spacing and minimal aggregation.

General Information

  • CAS No. 2952895-31-5
  • Cat. No. CS-0148098
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₉F₅O₆
  • Molecular Weight 402.31
  • Synonym(s) None
  • SMILES COCCOCCOCCOCCC(OC1=C(F)C(F)=C(F)C(F)=C1F)=O

Computational Chemistry Data

  • TPSA   63.22
  • LogP   2.3738
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   13

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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