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CS-W001157 4
Total: USD 88.00

m-PEG4-PFP ester

  • CAS No. 2952895-31-5

  • Cat. No. CS-0148098
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

m-PEG4-PFP ester|CS-0148098

Structure of 2952895-31-5

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General Information

  • CAS No. 2952895-31-5
  • Cat. No. CS-0148098
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₉F₅O₆
  • Molecular Weight 402.31
  • Synonym(s) None
  • SMILES COCCOCCOCCOCCC(OC1=C(F)C(F)=C(F)C(F)=C1F)=O

Description

m-PEG4-PFP ester features a hydrophilic PEG4 spacer flanked by a reactive pyridine-2,4-difluorophenyl (PFP) ester group, enabling efficient conjugation to primary amines under mild conditions. This bench-stable reagent facilitates site-specific labeling of biomolecules with minimal aggregation and enhanced solubility in aqueous environments.

Application

m-PEG4-PFP ester serves as a stable, water-soluble coupling reagent for amine functionalization, enabling efficient conjugation under physiological conditions. Its PFP ester moiety reacts selectively with primary amines to form robust amide bonds, while the central m-PEG4 spacer provides enhanced solubility and reduced steric hindrance. Ideal for bioconjugation workflows requiring precise spacing and minimal aggregation.

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   63.22
  • LogP   2.3738
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   13

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