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CS-W001157 4
Total: USD 88.00

2-(Pyrrolidin-1-yl)ethanol

  • CAS No. 2955-88-6

  • Cat. No. CS-W011235
  • Molecule weight115.18
  • Purity≥98%
  • MDL No.MFCD00003181

*For research and further manufacturing use only, not for direct human use.

2-(Pyrrolidin-1-yl)ethanol|CS-W011235

Structure of 2955-88-6

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General Information

  • CAS No. 2955-88-6
  • Cat. No. CS-W011235
  • Purity ≥98%
  • MDL No. MFCD00003181
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO
  • Molecular Weight 115.18
  • Synonym(s) 1-Pyrrolidineethanol
  • SMILES OCCN1CCCC1

Description

2-(Pyrrolidin-1-yl)ethanol is a bench-stable, moisture-tolerant amine featuring a pyrrolidine ring linked to an ethanolic chain. This polar, electron-rich scaffold integrates readily into synthetic workflows, serving as a key building block for bioactive molecules and functional polymers.

Application

2-(Pyrrolidin-1-yl)ethanol serves as a versatile bifunctional building block in synthetic chemistry, enabling efficient construction of nitrogen-containing heterocycles and amine-functionalized scaffolds. Its pyrrolidine moiety offers favorable solubility and nucleophilicity, while the primary alcohol facilitates derivatization via esterification, etherification, or oxidation. The compound exhibits excellent bench stability and compatibility with diverse reaction conditions, making it a practical choice for medicinal chemistry lead optimization and process-scale synthesis.

Synthesis

  • Route1
    • null|null
      123-75-1
    • null|null
      107-07-3
    • ~85%
    • In-stock
      2-(Pyrrolidin-1-yl)ethanol|CS-W011235
      2955-88-6

    References

    • Pandey; Kumaraswamy; Yella Reddy Tetrahedron, 1992 , vol. 48, # 38 p. 8295 - 8308
  • Route2
    • null|null
      123-75-1
    • null|null
      540-51-2
    • ~83%
    • In-stock
      2-(Pyrrolidin-1-yl)ethanol|CS-W011235
      2955-88-6

    References

    • JE IL PHARMACEUTICAL CO., LTD. Patent: WO2007/102679 A1, 2007 ; Location in patent: Page/Page column 106 ; WO 2007/102679 A1
  • Route3
    • In-stock
      β-Pyrrolidinoethyl chloride Hydrochloride|CS-D1148
      7250-67-1
    • null|null
      107-19-7
    • ~%
    • In-stock
      2-(Pyrrolidin-1-yl)ethanol|CS-W011235
      2955-88-6
    • 1-(2-(Prop-2-yn-1-yloxy)ethyl)pyrrolidine|CS-0947657
      1437774-68-9

    References

    • WO2013/72694 A1, ; Page/Page column 131; 132 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   0.0745
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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